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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
135
Publications with fulltext
Open Access
53 %
Mots clés
Thérapie génique
Glial cells
Cell culture model
Myostatin
Skeletal muscle
Antisense oligonucleotides
Cell penetrating peptide
Mouse models
Oligodendrocytes
Oligodendrocyte
CONGENITAL MYATHENIC SYNDROME
Glucocorticoid-receptor
CRISPRi
Cell model
Dystrophie myotonique
Myotonic Dystrophy Type 1
Brain dysfunction
PacBio
Myelin
Acute coronary syndrome
Glutamate
Gene editing
RNA biology
Quantitative microdialysis
Astrocyte
GSK3
RNA interference
CTG repeats
Desmin
Transcriptomics
Dystrophie Myotonique
DMSXL mice
In vivo
Intermediate filament
Glucocorticoids
Transgenic mouse
AAV
KNOCKOUT MICE
Acetylcholinesterase knockout mouse
Gene Therapy
Brain
Exercice
Central nervous system
DMPK
Exercise
Endurance training
ARN
Myotonic dystrophy mouse models
Acetylcholinesterase deficiency
Motoneuron
Expression
Long read sequencing
Dynamin 2
Knockout
Mouse model
Mice
CTG repeat instability
PCR
BIOLOGIE MOLECULAIRE
Neuron
Gene therapy
Myotonic Dystrophy
Muscle
Male
Myotonic dystrophy type 1
Trinucleotide Repeat Expansion
Heart failure
RNA splicing
Animals
Therapy
Heart
Humans
Antisense oligonucleotide
Maximal force
CMS
Myotonic dystrophy
Aging
Dystrophin
Alternative splicing
Cytoskeleton
Fibrosis
MBNL
Duchenne muscular dystrophy
ACETYLCHOLINESTERASE
Dilated cardiomyopathy
Autophagy
CRISPR/Cas9
Cardiac muscle
DM1
GABA
Myotonic Dystrophy type 1
Transgenic mouse model
CTG repeat contractions
Muscular dystrophy
Hypoxia
Diaphragm
Genotype phenotype correlation
Astrocytes
Trinucleotide repeat expansion
Centronuclear myopathy